Puppy need a series of FOUR DAPP vaccinations.
I will provide your puppy with the first puppy vaccination (when puppies are approx 6-7 weeks old). 
Your puppy will need three more puppy vaccination boosters. A 3-4 week interval between each vaccination is recommended by the vaccine manufacturer.

Professional Pet Care Topics: 

 American Veterinary Medical Association

Puppihood Vaccination and Deworming

4 wks               deworm

approx 6 wks   DAPP*, deworm

approx 9 wks   initial exam with vet, deworm, microchip insertion, fecal exam

After picking-up puppy from the breeder, new owner should take puppy for vet visit within 3 business days (vet visit important to establish care with a vet; vet should perform a basic exam, administer 2nd DAPP* puppy vaccination, possible blood labs and/or fecal exam).  Breeder must receive documentation of this visit in order to activate the health guarantee.

approx 12 wks  DAPP*, deworm, fecal

approx16 wks   DAPP*, deworm, rabies virus vaccine, (and fecal exam if vet deems necessary)

approx 6 mo    spay/neuter (before puppy becomes sexually mature)

* Nobivac® Canine 1-DAPPv (Galaxy DA2PPv) prevents Canine Distemper, Adenovirus Type 1 (Hepatitis), Adenovirus Type 2 (Respiratory Disease), Parainfluenza, and Parvovirus; DAPP may also be referred to as DHPP.

It is recommended that a series of four DAPP vaccinations be given every three to four weeks starting at 6 weeks of age.  Typically, rabies vaccination is given at age 16 weeks.

Not all dogs need every vaccine. Your veterinarian will ask you questions about your dog’s lifestyle, environment, and travel to help tailor the perfect vaccination plan for him. AAHA’s Lifestyle-Based Vaccine Calculator uses factors such as whether your dog visits dog parks, groomers, competes in dog shows, swims in freshwater lakes, or lives on converted farmland to help you and your veterinarian develop your dog’s individualized vaccination plan. There are “core” and “noncore” vaccines. Vaccinations are designated as either core, meaning they are recommended for every dog, or noncore, which means they are recommended for dogs at risk for contracting a specific disease. However, your veterinarian may reclassify a “non-core” vaccine as “core” depending on your dog’s age, lifestyle, and where you live - for instance, in a region where Lyme disease is prevalent, that vaccine may be considered “core”. https://www.aaha.org/pet_owner/aaha_guidelines/aahas_canine_vaccination_guidelines.aspx

The following vaccinations are considered to be non-core vaccinations that your veterinarian may/may not recommend based upon the puppy’s risk of exposure.  Please educate yourself on the benefits and risks of non-core vaccines before bringing your puppy home.  

  • Bordetella bronchiseptica (kennel cough)

  • Borrelia burgdorferi (bacteria that causes Lyme disease)

  • Influenza (H3N8/H3N2)

  • Leptospira bacteria

Vaccination and Deworming Information

Provided by:  Dr. Suzanne Sheldon, French Broad Mobile Vet, Weaverville, NC (Nov. 2018)


We give pediatric vaccines to protect against common viruses and bacteria that can make these individuals critically ill.  All of the core vaccines that we use today have minimal side effects and are very effective against the pathogens.  Nonetheless, all vaccines have the potential to cause allergic reaction and that side effect is controllable with close monitoring by the owner at home the day of vaccination. 


A vaccine’s job is to induce an immunologic antibody response.  The first vaccine will produce memory cells that require repeated pathogen exposure to produce antibodies on a protective level to neutralize the threat.  We are giving a very minor version of the disease so a real threat can be eliminated without life threating consequences.  No vaccine is a 100% barrier from getting some level of clinical signs if exposed to the pathogen.  We just want to mitigate the severity of disease. 


Just prior to birth, the mother produces the first milk, colostrum, which is composed of her antibodies and nourishing proteins for the first few weeks of life.  These essential protectors are absorbed from the gut in the first 24 hours of life.  It serves to protect the naïve newborn but we don’t know the quality of mom’s colostrum, if the neonate got any at all, or if they did was it absorbed when ingested.  To complicate immunology…mom’s colostrum antibodies have a blocking effect on our vaccines.  So there is a major question of the colostrum’s benefit, when will it wane, when will pathogen risk start, and when should we start vaccine protection.  Listed above is the veterinary recommended protocol for answering all of those questions despite risk, unknown colostrum benefit versus vaccine block, and naivety of our patients.  This protocol has proven to be minimally risky and maximally beneficial for both the patients and affordable for the owners. 


Additionally, it should be expected that ALL dogs and cats get gastrointestinal parasites from their mother.  No matter what her fecal ova parasite evaluation says the mother is going to release parasite eggs due to the natural immunosuppressive aspects of pregnancy and lactation.  She can’t get around it and we really can’t prevent it.  So we deworm at each vaccine visit to lessen the overall worm burden to the neonates and lessen the ability for the worms to encyst in the GI lining of these juvenile pets in the first place.  Early in the puppy or kittenhood vaccine series I recommend checking a fecal sample for the abnormal parasites these pets are prone to pick up like giardia and coccidia.